General contact

Head Office
Novartis International AG
CH-4002 Basel

+41 61 324 11 11
+41 61 324 80 01
Monday - Friday,
8:30 - 17:00, GMT+1
(Central European Time)


Novartis International AG
Investor Relations
P.O. Box
CH-4002 Basel

+41 61 324 79 44


Global Media Relations
Eric Althoff
Basel, Switzerland

+41 61 324 7999

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Addressing the unmet needs of children

Ahead of the call from the World Health Organization and UNICEF for “child-sized” medicines, the Novartis Malaria Initiative started developing, in collaboration with Medicines for Malaria Venture,1 a sweet-tasting artemisinin-based combination therapy (ACT) specifically for children.2,3

Launched in 2009, the medicine is the first ACT meeting WHO requirements for a pediatric antimalarial. Palatable and easily dispersed in water, it eases administration and enables accurate dosing for children without the need for cutting or crushing tablets.

The medicine contains the same amount of active ingredients as the regular tablet2 and has the same safety profile2 but is an attractive alternative for children (weighing 5kg and above) who find it difficult to swallow crushed pills, and thus may not adhere to the treatment.

Since its launch, 300 million treatments have been delivered without profit to 40 countries, mainly in Africa, making it the first pediatric ACT to have been delivered in such large quantities.

Our pediatric treatment is the first:

  • Artemisinin-based combination therapy (ACT) specifically tailored for infants and children
  • Pediatric ACT approved by Swissmedic (2008)2
  • Pediatric ACT pre-qualified by the WHO (2009)4 and recommended for use in the WHO treatment guidelines5
  • Sweet-tasting antimalarial to mask the bitter taste of artemisinin
  1. Novartis Press Release. “Novartis and Medicines for Malaria Venture launch Coartem® Dispersible, the first ACT* developed for children suffering from malaria.” (2009)
  2. Abdulla S, Sagara I, Borrmann S, D'Alessandro U, Gonzalez R, Hamel M et al. Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: a randomised, single-blind, multicentre trial. Lancet 2008; 372(9652):1819-1827.
  3. Malaria Journal 2010, 9:298.
  4. WHO List of Prequalified Products. Available at:
  5. WHO Guidelines for the Treatment of Malaria: Third Edition (2015).